Activation of the coagulation cascade and the role of paravalvular

coagulation cascade  The coagulation process is characterised by a cascade of events which lead to the formation of a blood clot Proteins called clotting factors initiate reactions A prominent feature of the proteins involved in the blood coagulation cascade is the high degree of specificity that enzymes have for protein substrates and

Normal coagulation pathway represents a balance between the pro coagulant pathway COAGULATION CASCADE It has been traditionally classified into intrinsic and Video to Explain the Mode of Action of Coagulation Cascade © Bayer AG, 2020

The coagulation cascade results in the accumulation of platelets at the wound site and the formation of a fibrin clot which stems blood flow in order to limit Coagulation is a complicated biological phenomenon which maintains the hemostasis Abnormalities in the genes that regulate the coagulation factors cause